From Abstract:
“Opiates induce electrical silencing of POMC neurons resulting in hyperphagic obesity and dysmetabolic syndrome, mimicking senescence. Hence POMC neuronal pathophysiology becomes amplified organism-wide in a feed-forward loop.
Together these factors suggest that we are on the very threshold of new insights which have the potential to overhaul both our conceptual understandings and our clinical treatments. The purpose of this review is to bring together findings from widely disparate areas and to elucidate their relevance and overlap with research on the effects of long-term opiate dependence. Whilst opiate dependence is the primary focus these observations likely also pertain to other chemical dependencies.”
From Abstract
“Data show that lifetime opioid exposure, an interactive cardiovascular risk factor, particularly in women, is related to linear, quadratic, cubic and quartic functions of treatment duration and is consistent with other literature of accelerated ageing in patients with OD.”
I told the students that the election is being overwhelmed by the issue because my own party, the Democrats, don’t want to touch it. They are afraid their candidates will lose a big chunk of the youth and liberal base who support legalization/decriminalization in the legislatures and state referenda. Like laetrile in the 1970s (which was legalized in more than 20 states and was supposed to cure cancer but turned out to be useless apricot pits that simply deferred real and needed treatment), “medical” marijuana is backed up only anecdotally and never is compared to an “n” of other treatment modalities that would be prescribed by doctors.
The results show that any history of cannabis use was associated with an increased likelihood of reporting difficulty falling asleep, struggling to maintain sleep, experiencing non-restorative sleep, and feeling daytime sleepiness.
For more read… http://www.science20.com/news_articles/marijuana_use_linked_to_impaired_sleep_quality-137585
Australian ‘Bong Lung’ - UK on verge of steep lung disease rise in young adults - due to heavy spliff smoking?
Researchers believe high cannabis and tobacco use was the major cause of the aggressive and advanced emphysema, independent of any genetic susceptibility, as all the patients had normal levels of the genes alpha 1 antitrypsin and chymotypsin.
Deficiencies of these genes can lead to the development of lung disease in some people.
Studies across the globe have also begun to pick up on this advanced and severe emphysema affecting young to middle aged people who use illicit drugs. In Australia smoking cannabis through a bong device, has led to the rise of what experts are now calling 'bong lung.'
Read More here…. http://medicalxpress.com/news/2014-12-uk-verge-steep-lung-disease.html
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dontlegalisedrugs.org
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United Nations Office of Drugs & Crime: Drug Prevention & Treatment
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https://www.tga.gov.au/access-medicinal-cannabis-products
Access to medicinal cannabis products: steps to using access ...
https://www.tga.gov.au/access-medicinal-cannabis-products-steps-using-access-schemes
https://www.tga.gov.au/medicinal-cannabis-products-overview-regulation
https://www.tga.gov.au/form/medicinal-cannabis-products
United Nations: Drug Use and Health Outcomes
UNODC Drug Indicator Statistics
Presentations, Statements & Conference Resources from WFAD 2018 Forum
THE DRUG ADVISORY COUNCIL OF AUSTRALIA SUPPORTS
More detoxification & rehabilitation that gets illicit drug users drug free.
Court ordered and supervised detoxification & rehabilitation.
Less illicit drug users, drug pushers and drug related crimes.