Cannabis

December 20, 2018

We already know that cannabis lowers sperm count, but new research suggests that the drug actually causes genetic changes to the sperm itself — which might have implications for the health of a potential baby.

For a study published today in the journal Epigenetics, scientists at Duke University 

Think of your DNA as a list of instructions for making proteins, and genes as small subsets of that list. Our body has little chemical tags (called methyl groups) that get added to the DNA at specific regions, explains Susan Kay Murphy, a professor of gynecology at Duke and co-author of the study. These chemicals don’t mutate the genes themselves, but they do affect how they’re used, like deciding which instructions are followed and which aren’t.

Najari already counsels men who use marijuana regularly to cut back because of the effect on sperm count. “I think one of the important positive things about research like this is that it may further motivate men to change their health,” he adds. “It’s one thing to talk about sperm count, another when you’re talking about the potential health of the child.”

Both Najari and Murphy stress that future research needs to be done, and the Duke team is already working on follow-up studies. Are those changes reversible? Will they even end up affecting a potential baby? “

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A Massachusetts General Hospital (MGH) study finds that one month of abstaining from cannabis use resulted in measurable improvement in memory functions important for learning among adolescents and young adults who are regular cannabis users. The study published in the Journal of Clinical Psychiatry is one of the first to prospectively track over time changes in cognitive function associated with halting cannabis use. “Our findings provide two pieces of convincing evidence,” says Randi Schuster, PhD, director of Neuropsychology at the Center for Addiction Medicine in the MGH Department of Psychiatry, lead author of the paper. “The first is that adolescents learn better when they are not using cannabis. The second – which is the good news part of the story – is that at least some of the deficits associated with cannabis use are not permanent and actually improve pretty quickly after cannabis use stops.” 

For complete article https://www.massgeneral.org/about/pressrelease.aspx?id=2308

October 2018 By Maria Kohut  Fact checked by Jasmin Collier

Authorities are legalizing cannabis, particularly for medicinal use, in an increasing number of states. Many people stand by its alleged benefits, but new research warns that frequent use may lead to the "disabling" symptoms of cannabis withdrawal syndrome.

The researchers also note that cannabis withdrawal symptoms appeared to be linked with mental disability and a family history of depression.

Also, these symptoms were associated with a number of psychiatric disorders, including mood disorders, anxiety disorders (social phobia, agoraphobia, and panic disorder), personality disorders, and post-traumatic stress disorder

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Often featuring in the lower rungs of priority when it comes to determining the safety of a drug, the impact of a pharmaceutical on the freshwater environment can be significant on the health of lakes, rivers and those who reside nearby.

The gamut is wide and worrying – from limpets in the UK no longer able to cling on to rocks for survival as they “bathe in a soup” of antidepressants to Canadian male fish growing eggs in their testes after being exposed to the synthetic estrogen found in birth control pills.

These examples should serve as a reminder that when deeming a drug fit for market, we should research and factor in its impact on the environment and water systems.

As the tide of marijuana legalization seems to be steadily sweeping North America, it also highlights how the USA and Canada, with our shared watersheds and borderless water movement, need to put our heads together on this issue... There is also guidance to prevent these compounds from leeching into nearby water bodies and reaching its flora and fauna.

It’s hard to overstate the importance of fresh water to North America’s economy and peoples.

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