Cannabis

Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits.

Rossignoli MT1, Lopes-Aguiar C2, Ruggiero RN3, Do Val da Silva RA4, Bueno-Junior LS5, Kandratavicius L6, Peixoto-Santos JE7, Crippa JA8, Cecilio Hallak JE9, Zuardi AW10, Szawka RE11, Anselmo-Franci J12, Leite JP13, Romcy-Pereira RN14. Author information Abstract The prefrontal cortex (PFC), amygdala and hippocampus display a coordinated activity during acquisition of associative fear memories. Evidence indicates that PFC engagement in… Read More »Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits.

Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease, a Randomized Controlled Trial.

Naftali T1,2, Mechulam R3,4, Marii A5, Gabay G6,7, Stein A6,7, Bronshtain M6,7, Laish I6,7, Benjaminov F6,7, Konikoff FM6,7. Author information Abstract BACKGROUND: Cannabidiol (CBD) is an anti-inflammatory cannabinoid shown to be beneficial in a mouse model of IBD. Lacking any central effect, cannabidiol is an attractive option for treating inflammatory diseases. AIM: To assess the… Read More »Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease, a Randomized Controlled Trial.

US Adult Illicit Cannabis Use, Cannabis Use Disorder, and Medical Marijuana Laws1991-1992 to 2012-2013

Deborah S. Hasin, PhD1,2,3; Aaron L. Sarvet, MPH1,2; Magdalena Cerdá, DrPH4; et alKatherine M. Keyes, PhD1,3; Malka Stohl, MS2; Sandro Galea, MD, DrPH5; Melanie M. Wall, PhD1,2,6 JAMA Psychiatry. Published online April 26, 2017. doi:10.1001/jamapsychiatry.2017.0724 Question  Are US state medical marijuana laws one of the underlying factors for increases in risk for adult cannabis use and cannabis use disorders seen since the early 1990s? Findings  In this analysis… Read More »US Adult Illicit Cannabis Use, Cannabis Use Disorder, and Medical Marijuana Laws1991-1992 to 2012-2013

Longitudinal influence of alcohol and marijuana use on academic performance in college students

Abstract BACKGROUND: Alcohol and marijuana are the two most abused substances in US colleges. However, research on the combined influence (cross sectional or longitudinal) of these substances on academic performance is currently scant. METHODS: Data were derived from the longitudinal 2-year Brain and Alcohol Research… Read More »Longitudinal influence of alcohol and marijuana use on academic performance in college students